Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 20/20 | 0.60 |
| ▸ | TPO | P07202 | 18/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27223604 | 0.87 | MPO (0.57) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749342 | 0.84 | MPO (0.53) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL27224051 | 0.84 | MPO (0.56) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL28896216 | 0.84 | MPO (0.47) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749315 | 0.82 | MPO (0.53) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL27224114 | 0.81 | MPO (0.72) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL27223497 | 0.81 | MPO (0.72) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749310 | 0.81 | MPO (0.72) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749312 | 0.81 | MPO (0.72) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL27223366 | 0.81 | MPO (0.72) | MPOTPOCYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-B | 2-thio-2, 3-dihydropyrimidine-4-one derivatives, pharmaceutical compositions, preparation methods and applications thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |