Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 5/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30829441 | 0.86 | — | — | |
| SCHEMBL28896246 | 0.82 | ACACB (0.36) | USP2SMN1; SMN2SCD5CYP11B2ACACB | |
| SCHEMBL28896482 | 0.82 | CYP4F2 (0.40) | USP2SMN1; SMN2SCD5CYP11B2USP30 | |
| SCHEMBL28896586 | 0.77 | USP2 (0.40) | USP2SMN1; SMN2SCD5CYP11B2ACACB | |
| SCHEMBL28896800 | 0.77 | USP2 (0.35) | USP2SMN1; SMN2ACACBRECQLGPR183 | |
| SCHEMBL5896294 | 0.77 | USP2 (0.41) | USP2SMN1; SMN2SCD5ACACBRECQL | |
| SCHEMBL15076445 | 0.76 | USP2 (0.43) | USP2SMN1; SMN2SCD5ACACBRECQL | |
| SCHEMBL31629602 | 0.76 | USP2 (0.40) | USP2SMN1; SMN2ACACBRECQLHPGD | |
| SCHEMBL20660514 | 0.76 | USP2 (0.38) | USP2SMN1; SMN2SCD5RECQLHPGD | |
| SCHEMBL23246690 | 0.75 | PKM (0.43) | USP2SMN1; SMN2SCD5CYP11B2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-B | 2-thio-2, 3-dihydropyrimidine-4-one derivatives, pharmaceutical compositions, preparation methods and applications thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |