Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12219347 | 0.83 | TSHR (0.35) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL12547206 | 0.83 | TSHR (0.39) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL7569750 | 0.81 | — | — | |
| SCHEMBL13604585 | 0.79 | ALDH1A1 (0.32) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL14933257 | 0.78 | — | — | |
| SCHEMBL15677578 | 0.78 | — | — | |
| SCHEMBL26327534 | 0.76 | CES1 (0.30) | — | |
| SCHEMBL118704 | 0.76 | ALDH1A1 (0.33) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL18413743 | 0.75 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL13447524 | 0.74 | ALDH1A1 (0.32) | ALDH1A1TSHRMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403584-B | 2-thio-2, 3-dihydropyrimidine-4-one derivatives, pharmaceutical compositions, preparation methods and applications thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115403584-A | 2-thio-2, 3-dihydropyrimidine-4-one derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-29 | — | — | CN | disclosed |