Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28897111 | 0.93 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1RAB9ATSHR | |
| SCHEMBL28437408 | 0.92 | CA12 (0.42) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL28439301 | 0.91 | KMT2A (0.45) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL28439299 | 0.91 | KMT2A (0.45) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL28442066 | 0.90 | CA12 (0.39) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL28434416 | 0.88 | CA12 (0.45) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL28443111 | 0.88 | CA12 (0.45) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL28442068 | 0.88 | CA12 (0.45) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL28431797 | 0.88 | CA12 (0.45) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL28443099 | 0.87 | CA12 (0.42) | KMT2AMEN1ALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386261-A | Coumarin derivatives, preparation method thereof and application thereof in cancer treatment | 利德发现中心有限责任公司 | 2020-07-07 | — | — | CN | claimed |
| CN-111386261-A | Coumarin derivatives, preparation method thereof and application thereof in cancer treatment | 利德发现中心有限责任公司 | 2020-07-07 | — | — | CN | disclosed |