Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 4/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28443600 | 0.86 | KDM4E (0.32) | ALDH1A1L3MBTL1KDM4EMAPTMEN1 | |
| SCHEMBL28453316 | 0.78 | SLC22A12 (0.38) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL28442805 | 0.77 | SLC22A12 (0.35) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL28451078 | 0.76 | GAA (0.34) | ALDH1A1L3MBTL1KDM4EMAPTMEN1 | |
| SCHEMBL28450315 | 0.76 | DPP4 (0.35) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL28448832 | 0.76 | GAA (0.34) | ALDH1A1L3MBTL1KDM4EMAPTMEN1 | |
| SCHEMBL28440418 | 0.74 | GAA (0.34) | ALDH1A1L3MBTL1KDM4EMAPTMEN1 | |
| SCHEMBL28448590 | 0.74 | GAA (0.37) | ALDH1A1L3MBTL1KDM4EMAPTMEN1 | |
| SCHEMBL28444818 | 0.74 | MEN1 (0.33) | ALDH1A1L3MBTL1KDM4EMAPTMEN1 | |
| SCHEMBL28444756 | 0.74 | MAPT (0.34) | ALDH1A1L3MBTL1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689928-B | Quinoline derivative and preparation method and application thereof | 山东省联合农药工业有限公司 | 2020-05-26 | — | — | CN | claimed |
| CN-108689928-B | Quinoline derivative and preparation method and application thereof | 山东省联合农药工业有限公司 | 2020-05-26 | — | — | CN | disclosed |