Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447787 | 0.84 | KMT2A (0.40) | KMT2ASMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL28445007 | 0.84 | KMT2A (0.40) | KMT2ASMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL32670661 | 0.77 | TDP1 (0.50) | KMT2AALDH1A1LMNATDP1KDM4E | |
| SCHEMBL28451372 | 0.76 | GAA (0.49) | KMT2ASMN1; SMN2ALDH1A1TDP1BCL9 | |
| SCHEMBL6363966 | 0.74 | KDM4E (0.50) | KMT2ASMN1; SMN2ALDH1A1TOP2ATDP1 | |
| SCHEMBL4077346 | 0.73 | KMT2A (0.53) | KMT2ASMN1; SMN2ALDH1A1TOP2ATDP1 | |
| SCHEMBL1013795 | 0.72 | KMT2A (0.58) | KMT2ASMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL29199525 | 0.72 | KMT2A (0.43) | KMT2ASMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL15558412 | 0.72 | MEN1 (0.57) | KMT2ASMN1; SMN2TOP2AKDM4EMEN1 | |
| SCHEMBL31047331 | 0.70 | TDP1 (0.53) | KMT2AALDH1A1LMNATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111479813-B | Triazolobenzazepines as vasopressin V1A receptor antagonists | 吉瑞工厂 | 2023-03-21 | — | — | CN | disclosed |
| CN-111479813-A | Triazolobenzazepines as vasopressin V1A receptor antagonists | 吉瑞工厂 | 2020-07-31 | — | — | CN | disclosed |