Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820288 | 1.00 | TDP1 (0.53) | TDP1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL32670661 | 0.85 | TDP1 (0.50) | TDP1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7351987 | 0.85 | TDP1 (0.50) | TDP1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6237111 | 0.85 | TDP1 (0.50) | TDP1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL17276050 | 0.84 | ALDH1A1 (0.49) | TDP1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL3308030 | 0.84 | TDP1 (0.49) | TDP1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL215837 | 0.83 | TDP1 (0.67) | TDP1ALDH1A1HTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL25313666 | 0.82 | ALDH1A1 (0.47) | TDP1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL15220550 | 0.81 | TDP1 (0.56) | TDP1ALDH1A1MEN1KMT2ATTR | |
| SCHEMBL30152985 | 0.80 | TDP1 (0.45) | TDP1ALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149189-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-07-18 | — | — | WO | disclosed |