Uridine

Uridine

SCHEMBL28898119

O=P(O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O.O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 15/20 0.79
SLC28A1 O00337 1/20 0.76
SLC28A2 O43868 1/20 0.76
SLC29A1 Q99808 1/20 0.76
SLC28A3 Q9HAS3 1/20 0.76
P2RY6 Q15077 10/20 0.75
P2RY4 P51582 8/20 0.75
P2RY14 Q15391 3/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine SCHEMBL28456453 1.00 P2RY2 (0.79) P2RY2SLC28A1SLC28A2SLC29A1SLC28A3
Uridine SCHEMBL29482406 1.00 P2RY2 (0.79) P2RY2SLC28A1SLC28A2SLC29A1SLC28A3
Uridine SCHEMBL29077342 0.99 P2RY2 (0.77) P2RY2SLC28A1SLC28A2SLC29A1SLC28A3
Uridine SCHEMBL15321443 0.99 P2RY2 (0.80) P2RY2SLC28A1SLC28A2SLC29A1SLC28A3
Uridine SCHEMBL4308217 0.99 P2RY2 (0.80) P2RY2SLC28A1SLC28A2SLC29A1SLC28A3
Uridine SCHEMBL29523645 0.99 P2RY2 (0.80) P2RY2SLC28A1SLC28A2SLC29A1SLC28A3
Uridine SCHEMBL28201123 0.95 P2RY2 (0.77) P2RY2SLC28A1SLC28A2SLC29A1SLC28A3
Uridine SCHEMBL30293967 0.94 SLC28A1 (0.81) P2RY2SLC28A1SLC28A2SLC29A1SLC28A3
Uridine SCHEMBL4244 0.94 SLC28A1 (0.81) P2RY2SLC28A1SLC28A2SLC29A1SLC28A3
Uridine SCHEMBL30205276 0.94 P2RY2 (0.73) P2RY2SLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111662350-B Preparation method of green intelligent high-purity diquafosol tetrasodium 南京宸翔医药研究有限责任公司 2022-06-07 CN disclosed
CN-111662350-A Preparation method of green intelligent high-purity diquafosol tetrasodium 南京宸翔医药研究有限责任公司 2020-09-15 CN disclosed