Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Uridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 known ✓ | P41231 | 17/20 | 0.73 |
| ▸ | P2RY6 known ✓ | Q15077 | 12/20 | 0.68 |
| ▸ | P2RY4 known ✓ | P51582 | 9/20 | 0.67 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.70 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.70 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.70 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Uridine SCHEMBL22635937 | 0.95 | SLC28A1 (0.74) | P2RY2SLC28A1SLC28A2SLC29A1SLC28A3 | |
| Uridine SCHEMBL29523645 | 0.95 | P2RY2 (0.80) | P2RY2SLC28A1SLC28A2SLC29A1SLC28A3 | |
| Uridine SCHEMBL15321443 | 0.95 | P2RY2 (0.80) | P2RY2SLC28A1SLC28A2SLC29A1SLC28A3 | |
| Uridine SCHEMBL4308217 | 0.95 | P2RY2 (0.80) | P2RY2SLC28A1SLC28A2SLC29A1SLC28A3 | |
| Uridine SCHEMBL28898119 | 0.94 | P2RY2 (0.79) | P2RY2SLC28A1SLC28A2SLC29A1SLC28A3 | |
| Uridine SCHEMBL29482406 | 0.94 | P2RY2 (0.79) | P2RY2SLC28A1SLC28A2SLC29A1SLC28A3 | |
| Uridine SCHEMBL28456453 | 0.94 | P2RY2 (0.79) | P2RY2SLC28A1SLC28A2SLC29A1SLC28A3 | |
| Uridine SCHEMBL29077342 | 0.93 | P2RY2 (0.77) | P2RY2SLC28A1SLC28A2SLC29A1SLC28A3 | |
| Uridine SCHEMBL28678575 | 0.92 | P2RY2 (0.71) | P2RY2SLC28A1SLC28A2SLC29A1SLC28A3 | |
| Uridine SCHEMBL10717264 | 0.92 | SLC28A1 (0.73) | P2RY2SLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710594-A | Method for synthesizing uridine diphosphate-6-azido-D-galactose | 中国科学院上海药物研究所 | 2023-02-24 | — | — | CN | disclosed |