Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | SLC10A1 | Q14973 | 9/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | WRN | Q14191 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28898134 | 0.93 | SLC10A1 (0.42) | GRM4SLC10A1LRRK2TSHRALDH1A1 | |
| SCHEMBL28898136 | 0.88 | SLC10A1 (0.42) | GRM4SLC10A1LRRK2 | |
| SCHEMBL28898130 | 0.86 | SLC10A1 (0.41) | GRM4SLC10A1LRRK2 | |
| SCHEMBL21408395 | 0.84 | SLC10A1 (0.46) | GRM4SLC10A1LRRK2ALDH1A1KDM4E | |
| SCHEMBL21408396 | 0.84 | SLC10A1 (0.46) | GRM4SLC10A1LRRK2ALDH1A1KDM4E | |
| SCHEMBL21428333 | 0.84 | GRM4 (0.43) | GRM4SLC10A1LRRK2TSHRALDH1A1 | |
| SCHEMBL28898148 | 0.83 | GRM4 (0.39) | GRM4SLC10A1LRRK2ALDH1A1KDM4E | |
| SCHEMBL21408335 | 0.82 | GRM4 (0.47) | GRM4SLC10A1LRRK2TSHRALDH1A1 | |
| SCHEMBL28898147 | 0.82 | TSHR (0.43) | SLC10A1TSHRALDH1A1POLBMAPT | |
| SCHEMBL28898160 | 0.81 | TSHR (0.42) | SLC10A1TSHRALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868026-B | Capsid protein assembly inhibitor containing N-heterocyclic five-membered ring, pharmaceutical composition and application thereof | 正大天晴药业集团股份有限公司 | 2022-11-25 | — | — | CN | disclosed |