Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC10A1 | Q14973 | 13/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28898160 | 0.93 | TSHR (0.42) | TSHRMAPTSMN1; SMN2LMNAUSP2 | |
| SCHEMBL28898154 | 0.92 | SLC10A1 (0.46) | TSHRSMN1; SMN2SLC10A1NPC1RAB9A | |
| SCHEMBL28898135 | 0.92 | TSHR (0.41) | TSHRMAPTSMN1; SMN2LMNAUSP2 | |
| SCHEMBL28898224 | 0.90 | TSHR (0.46) | TSHRMAPTSMN1; SMN2LMNAUSP2 | |
| SCHEMBL28898134 | 0.89 | SLC10A1 (0.42) | TSHRMAPTSMN1; SMN2LMNAUSP2 | |
| SCHEMBL28898150 | 0.89 | TSHR (0.42) | TSHRMAPTSMN1; SMN2LMNAUSP2 | |
| SCHEMBL28898131 | 0.88 | MAPT (0.42) | TSHRMAPTSMN1; SMN2LMNAUSP2 | |
| SCHEMBL21427912 | 0.86 | TSHR (0.44) | TSHRMAPTSMN1; SMN2LMNAUSP2 | |
| SCHEMBL21810153 | 0.84 | MAPT (0.51) | TSHRMAPTSMN1; SMN2LMNAUSP2 | |
| SCHEMBL30095297 | 0.84 | MAPT (0.51) | TSHRMAPTSMN1; SMN2LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868026-B | Capsid protein assembly inhibitor containing N-heterocyclic five-membered ring, pharmaceutical composition and application thereof | 正大天晴药业集团股份有限公司 | 2022-11-25 | — | — | CN | disclosed |