Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28898147 | 0.89 | TSHR (0.43) | TSHRMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28898160 | 0.88 | TSHR (0.42) | TSHRMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28898135 | 0.87 | TSHR (0.41) | TSHRMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28898154 | 0.87 | SLC10A1 (0.46) | TSHRSMN1; SMN2CYP1A2CYP2C9NPC1 | |
| SCHEMBL28898224 | 0.85 | TSHR (0.46) | TSHRMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL21427916 | 0.85 | TSHR (0.44) | TSHRMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28898134 | 0.84 | SLC10A1 (0.42) | TSHRMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28898131 | 0.83 | MAPT (0.42) | TSHRMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28959957 | 0.82 | GRM5 (0.41) | TSHRMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL21408421 | 0.81 | SLC10A1 (0.47) | TSHRMAPTALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868026-B | Capsid protein assembly inhibitor containing N-heterocyclic five-membered ring, pharmaceutical composition and application thereof | 正大天晴药业集团股份有限公司 | 2022-11-25 | — | — | CN | disclosed |