Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.35 |
| ▸ | SLC10A1 | Q14973 | 8/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28898141 | 0.84 | GRM4 (0.40) | GRM4FSCN1SLC10A1RAB9APGR | |
| SCHEMBL21427803 | 0.84 | GRM4 (0.41) | GRM4FSCN1SLC10A1RAB9ANPC1 | |
| SCHEMBL28902794 | 0.84 | GRM4 (0.41) | GRM4FSCN1SLC10A1RAB9ANPC1 | |
| SCHEMBL30294232 | 0.84 | GRM4 (0.41) | GRM4FSCN1SLC10A1RAB9ANPC1 | |
| SCHEMBL28898148 | 0.82 | GRM4 (0.39) | GRM4FSCN1SLC10A1PGRALDH1A1 | |
| SCHEMBL28898136 | 0.82 | SLC10A1 (0.42) | GRM4SLC10A1LRRK2 | |
| SCHEMBL30094001 | 0.81 | GRM4 (0.44) | GRM4FSCN1SLC10A1RAB9ANPC1 | |
| SCHEMBL21427892 | 0.81 | GRM4 (0.44) | GRM4FSCN1SLC10A1RAB9ANPC1 | |
| SCHEMBL28898138 | 0.81 | GRM4 (0.39) | GRM4SLC10A1PGRPOLBMAPT | |
| SCHEMBL28898134 | 0.81 | SLC10A1 (0.42) | GRM4SLC10A1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868026-B | Capsid protein assembly inhibitor containing N-heterocyclic five-membered ring, pharmaceutical composition and application thereof | 正大天晴药业集团股份有限公司 | 2022-11-25 | — | — | CN | disclosed |