SCHEMBL28898181

SCHEMBL28898181

C#CCCc1ccsc1C(=O)OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.48
NPC1 O15118 1/20 0.47
KDM4E B2RXH2 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
MEN1 O00255 4/20 0.46
CYP1A2 P05177 1/20 0.46
HPGD P15428 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MAPK10 P53779 4/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPK8 P45983 3/20 0.44
MAPK9 P45984 3/20 0.44
POLB P06746 2/20 0.44
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7941747 0.83 MAPK8 (0.39) KMT2AKDM4ENPSR1MAPK10ALDH1A1
SCHEMBL8636706 0.81 KMT2A (0.53) KMT2ANPC1KDM4ENPSR1MEN1
SCHEMBL6625082 0.81 KMT2A (0.57) KMT2ANPC1MEN1CYP1A2HPGD
SCHEMBL8634771 0.80 KMT2A (0.51) KMT2ANPC1KDM4ENPSR1MEN1
SCHEMBL27485588 0.80 KMT2A (0.51) KMT2ANPC1KDM4ENPSR1MEN1
SCHEMBL8630249 0.79 KMT2A (0.62) KMT2ANPC1KDM4EMEN1CYP1A2
SCHEMBL28114718 0.78 KMT2A (0.50) KMT2ANPC1KDM4ENPSR1MEN1
SCHEMBL28763196 0.78 KMT2A (0.54) KMT2ANPC1MEN1CYP1A2HPGD
SCHEMBL4683311 0.77 KMT2A (0.56) KMT2ANPC1KDM4ENPSR1MEN1
SCHEMBL23142270 0.77 KMT2A (0.49) KMT2ANPC1KDM4EMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115057803-B S- (methyl-d) 3 ) Synthesis method and application of phenyl sulfide substance 杭州师范大学 2023-11-24 CN disclosed
CN-115057803-A S- (methyl-d) 3 ) Synthetic method and application of phenylether substances 杭州师范大学 2022-09-16 CN disclosed