Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.90 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.90 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.90 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | STS | P08842 | 1/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | RXRB | P28702 | 1/20 | 0.56 |
| ▸ | RXRG | P48443 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.54 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557554 | 0.92 | PTPN2 (0.81) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| Hydrochloric Acid SCHEMBL28768913 | 0.91 | PTPN2 (0.79) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL12771465 | 0.89 | PTPN1 (0.88) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL28454201 | 0.88 | PTPN2 (0.74) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL1317618 | 0.86 | PTPN2 (0.71) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL29971632 | 0.86 | PTPN2 (0.71) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL29686111 | 0.86 | PTPN2 (0.71) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL12648835 | 0.86 | PTPN2 (0.83) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL8283575 | 0.85 | PTPN2 (0.81) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL2378725 | 0.85 | PTPN2 (0.81) | PTPN1PTPN2PTPN6ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945470-B | Tripeptide epoxy ketone compound constructed by heterocycle, preparation and application | 浙江大学 | 2020-08-11 | — | — | CN | disclosed |