SCHEMBL28898394

SCHEMBL28898394

N#Cc1cc[c]cc1OC(F)F

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1420151 0.85 KCNN4 (0.34) KCNN4
SCHEMBL900766 0.78 DRD1 (0.30)
SCHEMBL900876 0.76 KMT2A (0.34)
SCHEMBL1066799 0.75 PDE2A (0.33)
SCHEMBL29979131 0.75 KCNN4 (0.48) KCNN4
SCHEMBL233007 0.75 ALDH1A1 (0.44)
SCHEMBL8013768 0.75 KCNN4 (0.48) KCNN4
SCHEMBL3530578 0.74 FFAR1 (0.43) KCNN4
SCHEMBL1180592 0.74 SLC22A12 (0.34)
SCHEMBL403016 0.73 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111655700-A Benzyl-, (pyridin-3-yl) methyl-or (pyridin-4-yl) methyl-substituted oxadiazolopyridine derivatives as ghrelin O-acyltransferase (GOAT) inhibitors 勃林格殷格翰国际有限公司 2020-09-11 CN disclosed