Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30805636 | 0.85 | USP2 (0.38) | USP2SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL9185491 | 0.75 | USP2 (0.41) | USP2SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL3277549 | 0.72 | USP2 (0.46) | USP2SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL3354765 | 0.72 | USP2 (0.40) | USP2SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL1838102 | 0.71 | PREP (0.37) | USP2SMN1; SMN2HPGDCHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL28241841 | 0.70 | PREP (0.36) | USP2SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL28856336 | 0.70 | CHRM2 (0.38) | USP2SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL27423893 | 0.70 | USP2 (0.44) | USP2SMN1; SMN2HPGDCHRM2CHRM1 | |
| SCHEMBL8120965 | 0.69 | ESR2 (0.38) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL27647283 | 0.69 | USP2 (0.35) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113906025-A | Imidazopyridine derivatives as IL-17 modulators | UCB生物制药有限责任公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-111601799-A | Fused imidazole derivatives as Il-17 modulators | UCB生物制药有限责任公司 | 2020-08-28 | — | — | CN | disclosed |