Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 7/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28960015 | 0.83 | ITGB1 (0.31) | SMN1; SMN2 | |
| SCHEMBL28500536 | 0.79 | ALDH1A1 (0.42) | NPBWR1ALDH1A1HPGDNPC1MITF | |
| SCHEMBL28898520 | 0.68 | HTT (0.42) | GAAALDH1A1NPC1MITFHTT | |
| SCHEMBL28509663 | 0.64 | ALDH1A1 (0.43) | NPBWR1GAAALDH1A1HPGDNPC1 | |
| SCHEMBL29452092 | 0.62 | HTT (0.42) | GAAALDH1A1HPGDNPC1MITF | |
| SCHEMBL29451526 | 0.59 | ALDH1A1 (0.44) | ALDH1A1HPGDNPC1MITFHTT | |
| SCHEMBL29451369 | 0.59 | ALDH1A1 (0.44) | ALDH1A1HPGDNPC1MITFHTT | |
| SCHEMBL29451492 | 0.59 | ALDH1A1 (0.44) | ALDH1A1HPGDNPC1MITFHTT | |
| SCHEMBL25418672 | 0.58 | HCAR2 (0.36) | — | |
| SCHEMBL29451464 | 0.58 | ALDH1A1 (0.46) | NPBWR1GAAALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947681-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-109641844-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2022-11-01 | — | — | CN | disclosed |