Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28898662 | 0.81 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3MAOBCYP2A6 | |
| SCHEMBL28898650 | 0.78 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3MAOBNPC1 | |
| SCHEMBL28898661 | 0.78 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3MAOBCYP3A4 | |
| SCHEMBL10688286 | 0.76 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3MAOBNPC1 | |
| SCHEMBL10688281 | 0.76 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3MAOBNPC1 | |
| SCHEMBL10552479 | 0.75 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3MAOBNPC1 | |
| SCHEMBL9263317 | 0.75 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3MAOBNPC1 | |
| SCHEMBL11573583 | 0.75 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3MAOBNPC1 | |
| SCHEMBL2689310 | 0.74 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3MAOBCYP3A4 | |
| SCHEMBL2689879 | 0.71 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3MAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385877-B | Dihydrofuran-2-one compound and preparation method thereof | 嘉兴学院 | 2024-02-23 | — | — | CN | disclosed |
| CN-115385877-A | Dihydrofuran-2-ketone compound and preparation method thereof | 嘉兴学院 | 2022-11-25 | — | — | CN | disclosed |