Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.56 |
| ▸ | PTAFR | P25105 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25354888 | 0.82 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3PTAFRDRD1 | |
| SCHEMBL28898662 | 0.82 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL28898661 | 0.81 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL28898685 | 0.78 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3PTAFRNPC1 | |
| SCHEMBL28463514 | 0.72 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3PTAFRGAA | |
| SCHEMBL28412359 | 0.72 | MAOB (0.35) | PTAFRMEN1KMT2AKDM1AMAOB | |
| SCHEMBL25356284 | 0.72 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3PTAFRMEN1 | |
| SCHEMBL2689197 | 0.71 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3DRD1HTR2C | |
| SCHEMBL25354698 | 0.70 | SLC6A4 (0.54) | SLC6A2SLC6A4SLC6A3PTAFRDRD1 | |
| SCHEMBL28801266 | 0.70 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385877-A | Dihydrofuran-2-ketone compound and preparation method thereof | 嘉兴学院 | 2022-11-25 | — | — | CN | disclosed |