Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28450592 | 0.96 | CYP17A1 (0.33) | CYP17A1NFKB1QPCTHSD17B10QPCTL | |
| SCHEMBL28450868 | 0.91 | CYP17A1 (0.34) | CYP17A1 | |
| Bromide SCHEMBL28461562 | 0.77 | CYP17A1 (0.31) | CYP17A1 | |
| SCHEMBL15357788 | 0.76 | — | — | |
| SCHEMBL1136783 | 0.76 | CYP17A1 (0.34) | CYP17A1 | |
| Hydrochloric Acid SCHEMBL29033672 | 0.74 | CYP17A1 (0.31) | CYP17A1 | |
| SCHEMBL20474465 | 0.72 | NFKB1 (0.32) | NFKB1QPCTHSD17B10QPCTL | |
| SCHEMBL28768694 | 0.69 | HSD17B10 (0.34) | CYP17A1NFKB1QPCTHSD17B10QPCTL | |
| Bromide SCHEMBL28854105 | 0.69 | CYP17A1 (0.34) | CYP17A1NFKB1QPCTHSD17B10QPCTL | |
| SCHEMBL28067799 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444710-A | Nonmetal dynamic iminium polyion liquid catalyst and preparation method and application method thereof | 武汉工程大学 | 2023-07-18 | — | — | CN | claimed |
| CN-109364993-B | For catalytic conversion of CO at normal pressure2Polyion liquid catalyst and preparation method thereof | 太原理工大学 | 2021-03-30 | — | — | CN | claimed |
| CN-111644073-A | CO (carbon monoxide)2/N2Preparation method and application of separation membrane material | 太原理工大学 | 2020-09-11 | — | — | CN | claimed |
| CN-111514932-A | Preparation method and application of polyion liquid catalyst | 太原理工大学 | 2020-08-11 | — | — | CN | claimed |
| CN-116444710-A | Nonmetal dynamic iminium polyion liquid catalyst and preparation method and application method thereof | 武汉工程大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-109364993-B | For catalytic conversion of CO at normal pressure2Polyion liquid catalyst and preparation method thereof | 太原理工大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-109364993-B | For catalytic conversion of CO at normal pressure2Polyion liquid catalyst and preparation method thereof | 太原理工大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-111644073-A | CO (carbon monoxide)2/N2Preparation method and application of separation membrane material | 太原理工大学 | 2020-09-11 | — | — | CN | disclosed |
| CN-111514932-A | Preparation method and application of polyion liquid catalyst | 太原理工大学 | 2020-08-11 | — | — | CN | disclosed |