Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL28124928 | 0.91 | CYP3A4 (0.70) | CYP3A4MAPTPOLBPARP1TSHR | |
| Decane SCHEMBL28230778 | 0.89 | MAPT (0.67) | CYP3A4MAPTPOLBPARP1TSHR | |
| Benzamide SCHEMBL22117133 | 0.87 | CYP3A4 (0.70) | CYP3A4MAPTPOLBPARP1TSHR | |
| Benzoic Acid SCHEMBL29094693 | 0.85 | TSHR (0.54) | MAPTTSHRCES2CES1MEN1 | |
| Benzamide SCHEMBL27660419 | 0.85 | PARP1 (0.73) | CYP3A4MAPTPOLBPARP1TSHR | |
| Benzamide SCHEMBL28182470 | 0.84 | CYP3A4 (0.59) | CYP3A4MAPTPOLBPARP1TSHR | |
| Benzoic Acid SCHEMBL28937524 | 0.84 | CES2 (0.54) | MAPTTSHRCES2CES1MEN1 | |
| Benzamide SCHEMBL2401802 | 0.82 | PARP1 (0.76) | CYP3A4MAPTPOLBPARP1TSHR | |
| Octadecanoic Acid Amide SCHEMBL29012582 | 0.82 | CES2 (0.62) | CYP3A4MAPTPOLBPARP1TSHR | |
| Benzamide SCHEMBL8383228 | 0.82 | CES2 (0.59) | CYP3A4MAPTPOLBPARP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111635387-B | Synthesis method of chromone derivative | 都创(上海)医药科技股份有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-111635387-A | Synthesis method of chromone derivative | 都创(上海)医药科技有限公司 | 2020-09-08 | — | — | CN | disclosed |