Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCND3 | P30281 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL28462345 | 0.95 | CDK4 (0.31) | CDK4CCND1CCND3CDK6 | |
| Methane SCHEMBL4832996 | 0.81 | CDK4 (0.40) | CDK4CCND1CCND3CDK6 | |
| Methane SCHEMBL4832629 | 0.81 | CDK4 (0.40) | CDK4CCND1CCND3CDK6 | |
| Methane SCHEMBL6943814 | 0.81 | CDK4 (0.40) | CDK4CCND1CCND3CDK6 | |
| Methane SCHEMBL28475491 | 0.79 | CCNE1 (0.31) | CCND1CDK6 | |
| Methane SCHEMBL4833545 | 0.75 | CDK4 (0.40) | CDK4CCND1CCND3 | |
| Methane SCHEMBL28473469 | 0.74 | CDK4 (0.32) | CDK4CCND1CCND3CDK6 | |
| Methane SCHEMBL28462333 | 0.74 | CCNE1 (0.31) | CCND1CDK6 | |
| Methane SCHEMBL4828675 | 0.73 | CDK2 (0.44) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL28899486 | 0.72 | CDK4 (0.38) | CDK4CCND1CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191857-B | 6-substituted pyrido [2,3-D ] pyrimidines as protein kinase inhibitors | 晟科药业（江苏）有限公司 | 2020-10-23 | — | — | CN | disclosed |