SCHEMBL6296907

SCHEMBL6296907

CC(C)(C)c1ccc(-c2nnc(-c3ccc(-c4ccc(-c5nnc(-c6ccc(C(C)(C)C)cc6)o5)cc4)cc3)o2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.72
RAB9A P51151 7/20 0.72
KDM4E B2RXH2 3/20 0.72
S1PR1 P21453 2/20 0.65
NR1H4 Q96RI1 1/20 0.55
EGFR P00533 1/20 0.54
KIF11 P52732 2/20 0.54
NOTUM Q6P988 1/20 0.53
POLB P06746 2/20 0.50
TP53 P04637 2/20 0.50
S1PR4 O95977 1/20 0.50
S1PR5 Q9H228 1/20 0.50
IKBKB O14920 2/20 0.49
SMN1; SMN2 Q16637 3/20 0.48
HPGD P15428 2/20 0.48
NFKB1 P19838 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
ALDH1A1 P00352 2/20 0.48
MAPT P10636 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104799 1.00 NPC1 (0.72) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL3293191 0.98 NPC1 (0.75) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL2623780 0.98 NPC1 (0.75) NPC1RAB9AKDM4ES1PR1NR1H4
Biphenyl SCHEMBL28899764 0.92 S1PR1 (0.67) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL28982567 0.92 S1PR1 (0.67) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL12570671 0.92 NPC1 (0.64) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL74782 0.92 S1PR1 (0.67) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL2623779 0.92 S1PR1 (0.67) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL10330362 0.92 NPC1 (0.64) NPC1RAB9AKDM4ES1PR1NR1H4
SCHEMBL31606600 0.92 NPC1 (0.64) NPC1RAB9AKDM4ES1PR1NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8421339-B2 Organic electroluminescent device, exposure device, process cartridge, image forming apparatus, display apparatus, and method for driving organic electroluminescent device FUJI XEROX CO., LTD. (JP) 2013-04-16 US disclosed
US-8421339-B2 Organic electroluminescent device, exposure device, process cartridge, image forming apparatus, display apparatus, and method for driving organic electroluminescent device FUJI XEROX CO., LTD. (JP) 2013-04-16 US disclosed
US-7910748-B2 Thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2011-03-22 US disclosed
US-7902382-B2 Thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2011-03-08 US disclosed
US-20100327779-A1 ORGANIC ELECTROLUMINESCENT DEVICE, EXPOSURE DEVICE, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, DISPLAY APPARATUS, AND METHOD FOR DRIVING ORGANIC ELECTROLUMINESCENT DEVICE FUJI XEROX CO., LTD. (JP) 2010-12-30 US disclosed
US-20100133995-A1 Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2010-06-03 US disclosed
US-20100137553-A1 Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2010-06-03 US disclosed
US-7659410-B2 Thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2010-02-09 US disclosed
US-20080238832-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE FUJI XEROX CO., LTD (JP) 2008-10-02 US disclosed
US-20070292681-A1 Organic electroluminescence device FUJI XEROX CO., LTD (JP) 2007-12-20 US disclosed
US-20070281076-A1 Organic electroluminescent device and production method thereof FUJI XEROX CO., LTD. (JP) 2007-12-06 US disclosed
US-20070252519-A1 Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2007-11-01 US disclosed
US-20070148493-A1 Organic electroluminescence device FUJI XEROX CO., LTD. 2007-06-28 US disclosed
US-7183009-B2 Organic electroluminescent element FUJI XEROX CO., LTD. (JP) 2007-02-27 US disclosed
US-6908638-B2 Organic electroluminescent element and method of manufacturing same MINOLTA CO., LTD. (JP) 2005-06-21 US disclosed
US-20010033347-A1 Display element and layered type display element MINOLTA CO., LTD. 2001-10-25 US disclosed
US-20010003601-A1 ORGANIC ELECTROLUMINECENT ELEMENT AND METHOD OF MANUFACTURING SAME MINOLTA CO., LTD. (JP) 2001-06-14 US disclosed
US-6180217-B1 Organic electroluminescent element MINOLTA CO., LTD. (JP) 2001-01-30 US disclosed
US-6060826-A Organic electroluminescent element having an excimer light irradiated positive electrode and method of manufacturing the same MINOLTA CO., LTD. (JP) 2000-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070252519-A1 Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium ARL1, NOD1, NLRP1 NPC1 1769/4885RAB9A 2145/4885KDM4E 3875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.