Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 9/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28677605 | 0.81 | IDO1 (0.52) | ALDH1A1CYP3A4TDP1APPMAPT | |
| SCHEMBL25397498 | 0.77 | IDO1 (0.52) | MAOBAPPLOXL2IDO1 | |
| SCHEMBL17484610 | 0.77 | AGXT (0.52) | ALDH1A1MAOBMAPTGAARAB9A | |
| SCHEMBL28150816 | 0.77 | IDO1 (0.52) | ALDH1A1TSHRMAOBAPPMAPT | |
| SCHEMBL2025672 | 0.76 | TSHR (0.52) | ALDH1A1TSHRTDP1L3MBTL1HIF1A | |
| Boric Acid SCHEMBL28556682 | 0.74 | TSHR (0.50) | ALDH1A1TSHRTDP1L3MBTL1HIF1A | |
| SCHEMBL6273725 | 0.74 | IDO1 (0.55) | MAOBAPPRAB9ASMN1; SMN2CA14 | |
| SCHEMBL14899719 | 0.73 | ALDH1A1 (0.50) | ALDH1A1CYP3A4GFERTSHRTDP1 | |
| SCHEMBL31532974 | 0.72 | MAOB (0.47) | MAOBLOXL2GAARAB9ASMN1; SMN2 | |
| SCHEMBL31468282 | 0.72 | ALDH1A1 (0.51) | ALDH1A1TSHRRAB9ASMN1; SMN2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403568-A | Quinazoline Aurora A covalent inhibitor and preparation method and application thereof | 中山大学 | 2022-11-29 | — | — | CN | disclosed |