Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.73 |
| ▸ | MAPT | P10636 | 8/20 | 0.73 |
| ▸ | GAA | P10253 | 8/20 | 0.73 |
| ▸ | MEN1 | O00255 | 7/20 | 0.69 |
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.69 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.69 |
| ▸ | GFER | P55789 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793935 | 1.00 | KMT2A (0.73) | KMT2AMAPTGAAMEN1RAB9A | |
| SCHEMBL28473939 | 0.84 | MAPT (1.00) | KMT2AMAPTGAAMEN1RAB9A | |
| SCHEMBL29794040 | 0.84 | MAPT (1.00) | KMT2AMAPTGAAMEN1RAB9A | |
| SCHEMBL28863297 | 0.82 | KMT2A (1.00) | KMT2AMAPTGAAMEN1RAB9A | |
| SCHEMBL28478378 | 0.81 | GAA (1.00) | KMT2AMAPTGAAMEN1RAB9A | |
| SCHEMBL28484863 | 0.80 | KMT2A (0.73) | KMT2AMAPTGAAMEN1RAB9A | |
| SCHEMBL28475909 | 0.78 | MAPT (0.84) | KMT2AMAPTGAAMEN1RAB9A | |
| SCHEMBL23657826 | 0.76 | KMT2A (0.76) | KMT2AMAPTGAAMEN1RAB9A | |
| SCHEMBL28479937 | 0.76 | KMT2A (0.72) | KMT2AMAPTGAAMEN1RAB9A | |
| SCHEMBL28474330 | 0.76 | KMT2A (0.70) | KMT2AMAPTGAAMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909082-B | Pyridine hydrazone derivatives, and preparation method and application thereof | 湖南大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-111909082-A | Pyridine hydrazone derivatives, and preparation method and application thereof | 湖南大学 | 2020-11-10 | — | — | CN | disclosed |