Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17807922 | 0.72 | HTR2A (0.44) | POLBHTR2AHTR2CTAAR1 | |
| SCHEMBL23783201 | 0.70 | VEGFA (0.47) | LMNAPOLBKDM4EALDH1A1MEN1 | |
| SCHEMBL30031969 | 0.70 | VEGFA (0.47) | LMNAPOLBKDM4EALDH1A1MEN1 | |
| SCHEMBL21197947 | 0.69 | HSD17B10 (0.51) | POLBGAAHTR2AALDH1A1HTR2C | |
| SCHEMBL31306573 | 0.69 | HSD17B10 (0.51) | POLBGAAHTR2AALDH1A1HTR2C | |
| SCHEMBL28596476 | 0.68 | CYP1A2 (0.30) | — | |
| SCHEMBL16117964 | 0.67 | TAAR1 (0.44) | POLBHTR2AHTR2CTAAR1CYP3A4 | |
| SCHEMBL16100600 | 0.66 | CYP3A4 (0.36) | LMNAPOLBGAAALDH1A1MEN1 | |
| SCHEMBL21822900 | 0.65 | PDE4A (0.46) | POLBHTR2AHTR2CTAAR1MAPT | |
| SCHEMBL28604821 | 0.65 | ALDH1A1 (0.38) | POLBKCNH2KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279370-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2022-11-01 | — | — | CN | disclosed |