Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27359783 | 0.84 | PTPN11 (0.39) | PTPN11HTTPSMB8LMNA | |
| SCHEMBL23663596 | 0.81 | PTPN11 (0.38) | PTPN11HTTLMNA | |
| SCHEMBL23208824 | 0.81 | PTPN11 (0.33) | PTPN11LMNA | |
| SCHEMBL27359779 | 0.78 | PSMB8 (0.46) | PTPN11HTTPSMB8LMNA | |
| SCHEMBL27359788 | 0.74 | PDE10A (0.38) | PSMB8LMNA | |
| SCHEMBL29802781 | 0.74 | PTPN11 (0.38) | PTPN11HTTLMNA | |
| SCHEMBL28622442 | 0.74 | PTPN11 (0.38) | PTPN11HTTLMNA | |
| SCHEMBL28615843 | 0.74 | PTPN11 (0.38) | PTPN11HTTLMNA | |
| SCHEMBL27359621 | 0.69 | PDE10A (0.37) | PSMB8LMNA | |
| SCHEMBL27359892 | 0.69 | CSNK2A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902415-A | Pharmaceutical compounds | 大冢制药株式会社 | 2020-11-06 | — | — | CN | disclosed |