Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28622442 | 0.97 | PTPN11 (0.38) | PTPN11HTTLMNA | |
| SCHEMBL23663596 | 0.83 | PTPN11 (0.38) | PTPN11HTTLMNA | |
| SCHEMBL27359783 | 0.83 | PTPN11 (0.39) | PTPN11HTTLMNA | |
| SCHEMBL28615843 | 0.79 | PTPN11 (0.38) | PTPN11HTTLMNA | |
| SCHEMBL28902124 | 0.74 | PTPN11 (0.34) | PTPN11HTTLMNA | |
| SCHEMBL27359779 | 0.73 | PSMB8 (0.46) | PTPN11HTTLMNA | |
| SCHEMBL23208916 | 0.72 | PTPN11 (0.34) | PTPN11 | |
| SCHEMBL27359788 | 0.70 | PDE10A (0.38) | LMNA | |
| SCHEMBL27359621 | 0.68 | PDE10A (0.37) | LMNA | |
| SCHEMBL27359778 | 0.67 | PSMB8 (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981268-A | Pyrimidine-4 (3H) -ketone heterocyclic compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-08-30 | — | — | CN | disclosed |