Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.64 |
| ▸ | MAOA | P21397 | 4/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.64 |
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902182 | 0.81 | MAOB (0.74) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL28902198 | 0.80 | MAOB (0.76) | MAOBMAOAADORA2BCA12CA9 | |
| SCHEMBL30787479 | 0.79 | MAOB (0.60) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL4971961 | 0.78 | MAOB (1.00) | MAOBMAOAADORA2BNPC1MAPT | |
| SCHEMBL30167102 | 0.77 | MAOB (1.00) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL28902170 | 0.77 | MAOB (1.00) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30167103 | 0.76 | MAOB (0.79) | MAOBMAOAADORA2BCA12CA9 | |
| SCHEMBL28902190 | 0.76 | MAOB (0.79) | MAOBMAOAADORA2BCA12CA9 | |
| SCHEMBL30787481 | 0.76 | MAOB (0.75) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30787457 | 0.74 | MAOB (0.76) | MAOBMAOACA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115246805-B | Chromone-aniline alpha-glucosidase inhibitor and preparation method and application thereof | 贵州医科大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-115246805-A | Chromone-aniline alpha-glucosidase inhibitor and preparation method and application thereof | 贵州医科大学 | 2022-10-28 | — | — | CN | disclosed |