Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441811 | 0.98 | ESR2 (0.47) | ESR2HTR2CNPC1CASP3RAB9A | |
| SCHEMBL28008442 | 0.95 | ESR2 (0.45) | ESR2HTR2CNPC1CASP3RAB9A | |
| SCHEMBL11190434 | 0.93 | ESR2 (0.54) | ESR2NPC1CASP3RAB9ASENP8 | |
| SCHEMBL11195824 | 0.91 | ESR2 (0.53) | ESR2NPC1CASP3RAB9ASENP8 | |
| SCHEMBL11196416 | 0.91 | ESR2 (0.44) | ESR2HTR2CNPC1CASP3RAB9A | |
| SCHEMBL11362512 | 0.88 | ESR2 (0.50) | ESR2HTR2CNPC1CASP3RAB9A | |
| SCHEMBL11195873 | 0.88 | ESR2 (0.50) | ESR2NPC1CASP3RAB9ASENP8 | |
| SCHEMBL11141822 | 0.87 | ESR2 (0.41) | ESR2NPC1CASP3RAB9ASENP8 | |
| SCHEMBL11193083 | 0.87 | ESR2 (0.49) | ESR2NPC1CASP3RAB9ASENP8 | |
| SCHEMBL11192882 | 0.87 | ESR2 (0.49) | ESR2NPC1CASP3RAB9ASENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119120038-A | Liquid crystal medium, liquid crystal display device containing same and compound | 默克专利股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-114144498-B | Liquid crystal medium, liquid crystal display device containing same and compound | 默克专利股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-110997871-B | Liquid crystal compound | 默克专利股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-111094512-B | Liquid crystal medium and liquid crystal display comprising same | 默克专利股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| EP-3679111-B1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2023-11-01 | — | — | EP | disclosed |
| EP-3679111-B1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2023-11-01 | — | — | EP | disclosed |
| US-11795398-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | MERCK PATENT GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| US-11795398-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | MERCK PATENT GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| US-20220228065-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2022-07-21 | — | — | US | disclosed |
| EP-3994234-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | Merck Patent GmbH (DE) | 2022-05-11 | — | — | EP | disclosed |
| US-7695777-B2 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CHISSON CORPORATION (JP) | 2010-04-13 | — | — | US | disclosed |
| US-7695777-B2 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CHISSON CORPORATION (JP) | 2010-04-13 | — | — | US | disclosed |
| US-20080075891-A1 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CHISSO CORPORATION | 2008-03-27 | — | — | US | disclosed |
| US-20080075891-A1 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CHISSO CORPORATION | 2008-03-27 | — | — | US | disclosed |
| US-20080075891-A1 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CHISSO CORPORATION | 2008-03-27 | — | — | US | disclosed |
| EP-1897928-A1 | Chlorofluorobenzene liquid crystal compound, liquid crystal composition and liquid crystal display device | CHISSO CORPORATION (JP) | 2008-03-12 | — | — | EP | disclosed |
| EP-0767772-B1 | NOVEL CHIRAL CYCLOHEXYL COMPOUNDS | SECR DEFENCE (GB) | 2000-08-30 | — | — | EP | disclosed |
| US-5853613-A | Chiral cyclohexyl compounds | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1998-12-29 | — | — | US | disclosed |
| EP-0767772-A1 | NOVEL CHIRAL CYCLOHEXYL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000710-A1 | NOVEL CHIRAL CYCLOHEXYL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1996-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080075891-A1 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CNKSR1, CLCN2, LEF1 | ESR2 528/4885HTR2C 716/4885NPC1 3055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.