Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11955735 | 0.84 | KDM4E (0.47) | TSHRKDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL1127591 | 0.82 | KDM4E (0.69) | TSHRKDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL28487967 | 0.82 | TSHR (0.62) | TSHRKDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL29389855 | 0.81 | TSHR (0.70) | TSHRKDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL8927648 | 0.81 | TSHR (0.70) | TSHRKDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL18050536 | 0.79 | TSHR (0.54) | TSHRKDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL11983357 | 0.78 | TSHR (0.53) | TSHRKDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL10900936 | 0.78 | TSHR (0.66) | TSHRKDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL30125169 | 0.75 | KMT2A (0.67) | TSHRKDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL3303791 | 0.75 | KMT2A (0.67) | TSHRKDM4ELMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727524-B | Internal electron donor compound and catalyst for catalyzing propylene polymerization | 中国石油天然气股份有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-108727524-B | Internal electron donor compound and catalyst for catalyzing propylene polymerization | 中国石油天然气股份有限公司 | 2020-08-07 | — | — | CN | disclosed |