Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4517094 | 0.88 | JAK2 (0.40) | DPP4DPP8DPP9LTA4HHSD11B1 | |
| SCHEMBL33526075 | 0.84 | NOS3 (0.42) | DPP4DPP8DPP9LTA4HNOS3 | |
| SCHEMBL10427141 | 0.84 | NOS3 (0.42) | DPP4DPP8DPP9LTA4HNOS3 | |
| SCHEMBL10633018 | 0.84 | NOS3 (0.42) | DPP4DPP8DPP9LTA4HNOS3 | |
| SCHEMBL1954285 | 0.84 | NOS3 (0.42) | DPP4DPP8DPP9LTA4HNOS3 | |
| SCHEMBL6088399 | 0.84 | NOS3 (0.42) | DPP4DPP8DPP9LTA4HNOS3 | |
| SCHEMBL868782 | 0.84 | NOS3 (0.42) | DPP4DPP8DPP9LTA4HNOS3 | |
| SCHEMBL867932 | 0.84 | NOS3 (0.42) | DPP4DPP8DPP9LTA4HNOS3 | |
| SCHEMBL8031217 | 0.84 | NOS3 (0.42) | DPP4DPP8DPP9LTA4HNOS3 | |
| SCHEMBL4941511 | 0.84 | NOS3 (0.42) | DPP4DPP8DPP9LTA4HNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110099869-B | Thermally responsive solution and method of use thereof | 阿克福特斯技术有限公司 | 2022-12-06 | — | — | CN | disclosed |