Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 20/20 | 0.52 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28904272 | 1.00 | AR (0.52) | ARPGRCYP2C19 | |
| SCHEMBL30104698 | 0.81 | AR (0.59) | ARPGR | |
| SCHEMBL26364958 | 0.81 | AR (0.59) | ARPGR | |
| SCHEMBL26364956 | 0.81 | AR (0.59) | ARPGR | |
| SCHEMBL28904318 | 0.77 | AR (0.45) | ARPGRCYP2C19 | |
| SCHEMBL28904265 | 0.77 | AR (0.51) | ARPGRCYP2C19 | |
| SCHEMBL3294915 | 0.70 | AR (0.48) | AR | |
| SCHEMBL21891632 | 0.70 | AR (0.71) | ARPGR | |
| SCHEMBL30104648 | 0.69 | AR (0.62) | ARPGR | |
| SCHEMBL26364959 | 0.69 | AR (0.62) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427028-A | Selective Androgen Receptor Covalent Antagonists (SARCA) and methods of use thereof | 田纳西大学研究基金会 | 2022-12-02 | — | — | CN | disclosed |