SCHEMBL30104698

SCHEMBL30104698

CC(=CC(=O)Nc1ccc(C#N)c(C(F)(F)F)c1)n1cc(F)cn1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 18/20 0.59
PGR P06401 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26364958 1.00 AR (0.59) ARPGR
SCHEMBL26364956 1.00 AR (0.59) ARPGR
SCHEMBL26365041 0.82 AR (0.57) ARPGR
SCHEMBL28904272 0.81 AR (0.52) ARPGR
SCHEMBL28904285 0.81 AR (0.52) ARPGR
SCHEMBL30104648 0.81 AR (0.62) ARPGR
SCHEMBL26364959 0.81 AR (0.62) ARPGR
SCHEMBL26364955 0.80 AR (0.51) AR
SCHEMBL21891632 0.78 AR (0.71) ARPGR
SCHEMBL30104708 0.78 AR (0.49) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4110322-A1 SELECTIVE ANDROGEN RECEPTOR COVALENT ANTAGONISTS (SARCAS) AND METHODS OF USE THEREOF University of Tennessee Research Foundation (US) 2023-01-04 EP disclosed