Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.60 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | PRF1 | P14222 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630228 | 0.81 | APP (0.81) | APPCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL30862485 | 0.80 | APP (0.70) | APPCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL29036191 | 0.80 | APP (0.70) | APPCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL5399485 | 0.78 | APP (0.94) | APPCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL30903823 | 0.78 | APP (0.94) | APPCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL30903820 | 0.78 | APP (0.94) | APPCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL30903822 | 0.78 | APP (0.94) | APPCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL3367944 | 0.77 | APP (0.76) | APPCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL7006689 | 0.77 | APP (0.91) | APPCYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL3364536 | 0.77 | APP (0.51) | APPCYP3A4CYP2A6CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174839-A | Lipid drop specific labeled fluorescent probe and synthetic method and application thereof | 四川大学华西医院 | 2021-01-05 | — | — | CN | disclosed |