SCHEMBL3364536

SCHEMBL3364536

Cc1ccccc1N(c1ccc(-c2ccc(-c3ccc(C=O)cc3)s2)cc1)c1ccccc1C

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.51
HSD17B1 P14061 4/20 0.43
HSD17B2 P37059 4/20 0.43
ALDH1A1 P00352 3/20 0.39
ALDH3A1 P30838 1/20 0.39
ALDH1A3 P47895 1/20 0.39
CYP2A6 P11509 3/20 0.38
CYP2A13 Q16696 1/20 0.38
MAPT P10636 2/20 0.37
CYP3A4 P08684 3/20 0.34
LMNA P02545 1/20 0.34
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
TSHR P16473 2/20 0.32
NQO2 P16083 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5182285 0.87 ALDH1A1 (0.50) ALDH1A1ALDH3A1ALDH1A3CYP2A6CYP2A13
SCHEMBL7750867 0.83 ALDH1A1 (0.50) ALDH1A1ALDH3A1ALDH1A3CYP2A6CYP2A13
SCHEMBL3364845 0.82 APP (0.72) APPHSD17B1HSD17B2ALDH1A1ALDH3A1
SCHEMBL3364532 0.81 APP (0.54) APPHSD17B1HSD17B2ALDH1A1ALDH3A1
SCHEMBL7750958 0.81 ALDH1A1 (0.47) APPALDH1A1ALDH3A1ALDH1A3CYP2A6
SCHEMBL3364925 0.77 APP (0.54) APPALDH1A1ALDH3A1ALDH1A3CYP2A6
SCHEMBL28904641 0.77 APP (0.60) APPHSD17B1HSD17B2ALDH1A1CYP2A6
SCHEMBL13358717 0.76 RELA (0.44) APPALDH1A1MAPTCYP3A4LMNA
SCHEMBL27816587 0.75 CYP2A6 (0.52) APPHSD17B1HSD17B2ALDH1A1CYP2A6
SCHEMBL7154196 0.75 ACHE (0.39) HSD17B1HSD17B2ALDH1A1MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL CRY1, DSG1, CRY2 APP 2553/4885HSD17B1 532/4885HSD17B2 613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.