Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070446 | 0.82 | LMNA (0.55) | LMNAKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL420412 | 0.81 | LMNA (0.54) | LMNAKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL6098517 | 0.80 | LMNA (0.61) | LMNAKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL7921928 | 0.78 | LMNA (0.51) | LMNAKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL5402595 | 0.78 | LMNA (0.55) | LMNAKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL13892301 | 0.78 | LMNA (0.63) | LMNAKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL6427335 | 0.77 | LMNA (0.54) | LMNAKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL19350976 | 0.77 | LMNA (0.50) | LMNAKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL13196349 | 0.76 | LMNA (0.49) | LMNAKMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL733288 | 0.75 | LMNA (0.47) | LMNAKMT2AALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |