SCHEMBL28905902

SCHEMBL28905902

COc1cc(-c2noc(C(F)(F)F)n2)ccc1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.51
ALDH1A1 P00352 2/20 0.50
HSD17B10 Q99714 2/20 0.50
TSHR P16473 2/20 0.50
CYP3A4 P08684 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
HDAC6 Q9UBN7 11/20 0.48
HDAC1 Q13547 6/20 0.48
HDAC5 Q9UQL6 4/20 0.48
HDAC8 Q9BY41 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
HDAC4 P56524 7/20 0.47
MEN1 O00255 1/20 0.46
TP53 P04637 1/20 0.46
NFKB1 P19838 1/20 0.46
MAPK1 P28482 1/20 0.46
NFKB2 Q00653 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2888002 0.82 HDAC4 (0.50) ALDH1A1TSHRCYP3A4TDP1HDAC6
SCHEMBL21903401 0.81 HDAC6 (0.52) NPSR1HDAC6HDAC1HDAC8HDAC4
SCHEMBL19801733 0.80 HDAC6 (0.55) HDAC6HDAC1HDAC5HDAC8HDAC4
SCHEMBL19864362 0.79 HDAC4 (0.50) HDAC6HDAC1HDAC5HDAC8HDAC4
Hydrochloric Acid SCHEMBL19859065 0.78 HDAC4 (0.49) HDAC6HDAC1HDAC5HDAC8HDAC4
SCHEMBL2228208 0.77 HDAC4 (0.52) NPSR1HDAC6HDAC8HDAC4MAPT
SCHEMBL7296994 0.77 HDAC6 (0.59) NPSR1HDAC6HDAC1HDAC8SMN1; SMN2
SCHEMBL28506637 0.77 HDAC1 (0.48) HDAC6HDAC1HDAC5HDAC8
SCHEMBL28504077 0.76 HDAC4 (0.48) HDAC6HDAC1HDAC5HDAC8HDAC4
SCHEMBL18824381 0.75 HDAC4 (0.66) HDAC6HDAC1HDAC8HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112004813-B Oxadiazole compounds for controlling phytopathogenic fungi PI工业有限公司 2024-03-29 CN claimed
CN-112004813-A Oxadiazole compounds for controlling phytopathogenic fungi PI工业有限公司 2020-11-27 CN claimed
CN-112004813-B Oxadiazole compounds for controlling phytopathogenic fungi PI工业有限公司 2024-03-29 CN disclosed
CN-112004813-A Oxadiazole compounds for controlling phytopathogenic fungi PI工业有限公司 2020-11-27 CN disclosed