SCHEMBL28905910

SCHEMBL28905910

COC(=O)C(C)(O)C(=O)N(c1ccccc1)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TP53 P04637 1/20 0.46
SRC P12931 1/20 0.45
MLYCD O95822 2/20 0.43
TRPM8 Q7Z2W7 2/20 0.43
KCNN4 O15554 1/20 0.41
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
ATM Q13315 1/20 0.39
ELANE P08246 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MAPT P10636 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28905917 0.80 NOTUM (0.46) ALDH1A1LMNASMN1; SMN2SRCKCNN4
SCHEMBL14399206 0.79 ALDH1A1 (0.56) ALDH1A1LMNASMN1; SMN2TP53MLYCD
SCHEMBL28905923 0.76 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2TP53SRCKCNN4
SCHEMBL14369615 0.76 ALDH1A1 (0.53) ALDH1A1LMNASMN1; SMN2TP53MLYCD
SCHEMBL17735706 0.75 ALDH1A1 (0.56) ALDH1A1LMNASMN1; SMN2TP53MLYCD
SCHEMBL12083381 0.72 SRC (0.70) ALDH1A1SRCKCNN4KMT2AELANE
SCHEMBL28905937 0.71 KMT2A (0.51) ALDH1A1SMN1; SMN2TP53MLYCDTRPM8
SCHEMBL28660961 0.71 ALDH1A1 (0.51) ALDH1A1LMNASMN1; SMN2TP53MLYCD
SCHEMBL2543696 0.70 ALDH1A1 (0.63) ALDH1A1LMNASMN1; SMN2TP53MLYCD
SCHEMBL5079915 0.70 ALDH1A1 (0.63) ALDH1A1LMNASMN1; SMN2TP53MLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115108901-A Synthetic method of alpha-hydroxycarboxylic acid compound 四川大学 2022-09-27 CN disclosed