Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28905953 | 1.00 | MME (0.47) | MMESLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL28453930 | 1.00 | MME (0.47) | MMESLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL9903748 | 0.80 | MME (0.44) | MMESLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL9902890 | 0.80 | MME (0.44) | MMESLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL934545 | 0.80 | MME (0.48) | MMESLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL7418074 | 0.78 | MME (0.56) | MMESLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL28237997 | 0.78 | SLC6A2 (0.50) | SLC1A3SLC1A2SLC1A1PTGS1CTSK | |
| SCHEMBL1811694 | 0.78 | SLC6A2 (0.50) | SLC1A3SLC1A2SLC1A1PTGS1CTSK | |
| SCHEMBL28914994 | 0.78 | SLC6A2 (0.50) | SLC1A3SLC1A2SLC1A1PTGS1CTSK | |
| SCHEMBL2561209 | 0.75 | NPC1 (0.45) | ALOX5PTGS1PTGS2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433160-B | Analgesic active compounds and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-06-30 | — | — | CN | disclosed |
| CN-115433160-A | Analgesic active compound and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-12-06 | — | — | CN | disclosed |