Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26903695 | 0.83 | MME (0.49) | MMESLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL8703272 | 0.83 | MME (0.49) | MMESLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL7418074 | 0.83 | MME (0.56) | MMESLC1A3SLC1A2SLC1A1PTGS1 | |
| SCHEMBL27790946 | 0.82 | TAAR1 (0.48) | MMESLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL5257074 | 0.81 | DPP4 (0.48) | MMESLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL17449974 | 0.81 | DPP4 (0.48) | MMESLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL28905941 | 0.80 | MME (0.47) | MMESLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL28905953 | 0.80 | MME (0.47) | MMESLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL28453930 | 0.80 | MME (0.47) | MMESLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL934618 | 0.78 | MME (0.46) | MMESLC1A3SLC1A2SLC1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454243-A2 | TETRAZOLE DERIVATIVES | Merck Serono SA (CH) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |