SCHEMBL28906001

SCHEMBL28906001

CC(C)c1nc(CNC=O)cs1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.43
ADORA2A P29274 1/20 0.40
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
DRD2 P14416 1/20 0.36
HTR2A P28223 1/20 0.36
HRH1 P35367 1/20 0.36
NPC1 O15118 1/20 0.36
RECQL P46063 1/20 0.36
ADH1B P00325 2/20 0.35
ADH1C P00326 2/20 0.35
ADH1A P07327 2/20 0.35
POLB P06746 1/20 0.35
TLR7 Q9NYK1 1/20 0.35
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33
PIK3CG P48736 1/20 0.33
ADH7 P40394 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7175958 0.79 CCR4 (0.43) SLC6A3ADORA2AALDH1A1MEN1KMT2A
SCHEMBL7179725 0.79 SLC6A3 (0.42) SLC6A3ADORA2AALDH1A1MEN1KMT2A
SCHEMBL902615 0.79 SLC6A3 (0.44) SLC6A3ADORA2AALDH1A1MEN1KMT2A
SCHEMBL13541114 0.78 SLC6A3 (0.41) SLC6A3ADORA2AALDH1A1MEN1KMT2A
SCHEMBL3361765 0.78 SLC6A3 (0.39) SLC6A3ADORA2AALDH1A1MEN1KMT2A
SCHEMBL10039948 0.77 KMT2A (0.49) ALDH1A1MEN1KMT2ANPC1SMN1; SMN2
Hydrochloric Acid SCHEMBL6090064 0.77 SLC6A3 (0.43) SLC6A3ADORA2AALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL16798712 0.77 SLC6A3 (0.43) SLC6A3ADORA2AALDH1A1MEN1KMT2A
SCHEMBL7187137 0.77 SLC6A3 (0.40) SLC6A3ADORA2AALDH1A1MEN1KMT2A
SCHEMBL28152375 0.77 SLC6A3 (0.43) SLC6A3ADORA2AALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115417829-A Preparation method of ritonavir enantiomer 武汉海特生物创新医药研究有限公司 2022-12-02 CN claimed
CN-115417829-A Preparation method of ritonavir enantiomer 武汉海特生物创新医药研究有限公司 2022-12-02 CN disclosed
CN-115417829-A Preparation method of ritonavir enantiomer 武汉海特生物创新医药研究有限公司 2022-12-02 CN disclosed