Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26097386 | 0.95 | MCHR1 (0.34) | MCHR1PDE2ACYP11B1CYP11B2 | |
| SCHEMBL26097337 | 0.93 | MCHR1 (0.34) | MCHR1PDE2ACYP11B1CYP11B2 | |
| SCHEMBL26097293 | 0.92 | MCHR1 (0.33) | MCHR1PDE2ACYP11B1CYP11B2 | |
| SCHEMBL24034805 | 0.89 | MCHR1 (0.34) | MCHR1PDE2ACYP11B1CYP11B2 | |
| SCHEMBL28906125 | 0.89 | MCHR1 (0.32) | MCHR1PDE2A | |
| SCHEMBL24034811 | 0.89 | MCHR1 (0.34) | MCHR1PDE2ACYP11B1CYP11B2 | |
| SCHEMBL24034690 | 0.88 | MCHR1 (0.36) | MCHR1PDE2ACYP11B1CYP11B2 | |
| SCHEMBL28906114 | 0.86 | — | — | |
| SCHEMBL24034813 | 0.84 | FEN1 (0.35) | MCHR1PDE2ACYP11B1CYP11B2 | |
| SCHEMBL30111757 | 0.84 | MCHR1 (0.33) | MCHR1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461337-A | Novel triazolyl derivatives as GABA A alpha 5 PAM | 豪夫迈·罗氏有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-115461337-A | Novel triazolyl derivatives as GABA A alpha 5 PAM | 豪夫迈·罗氏有限公司 | 2022-12-09 | — | — | CN | disclosed |