Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24034902 | 0.94 | MCHR1 (0.33) | MCHR1SIGMAR1PDE2A | |
| SCHEMBL24034842 | 0.93 | MCHR1 (0.33) | MCHR1SIGMAR1PDE2A | |
| SCHEMBL28906119 | 0.91 | MCHR1 (0.30) | MCHR1SIGMAR1 | |
| SCHEMBL24034705 | 0.91 | MCHR1 (0.32) | MCHR1SIGMAR1PDE2A | |
| SCHEMBL24034785 | 0.90 | SIGMAR1 (0.34) | MCHR1SIGMAR1PDE2A | |
| SCHEMBL28906127 | 0.89 | MCHR1 (0.34) | MCHR1PDE2A | |
| SCHEMBL26098150 | 0.89 | MCHR1 (0.33) | MCHR1SIGMAR1PDE2A | |
| SCHEMBL28906121 | 0.89 | CCNC (0.31) | — | |
| SCHEMBL24034840 | 0.88 | MCHR1 (0.34) | MCHR1SIGMAR1PDE2A | |
| SCHEMBL24034756 | 0.88 | MCHR1 (0.33) | MCHR1SIGMAR1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461337-A | Novel triazolyl derivatives as GABA A alpha 5 PAM | 豪夫迈·罗氏有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-115461337-A | Novel triazolyl derivatives as GABA A alpha 5 PAM | 豪夫迈·罗氏有限公司 | 2022-12-09 | — | — | CN | disclosed |