SCHEMBL28906222

SCHEMBL28906222

COc1cc(P)c(P(c2ccccc2)c2ccccc2)cc1OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA12 O43570 2/20 0.37
CA9 Q16790 2/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA7 P43166 1/20 0.37
CA14 Q9ULX7 1/20 0.37
NQO2 P16083 1/20 0.36
CYP1A1 P04798 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP1B1 Q16678 2/20 0.36
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
FGFR1 P11362 1/20 0.34
SRC P12931 1/20 0.34
NQO1 P15559 1/20 0.33
GAA P10253 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28906246 0.85 TDP1 (0.44) CYP3A4TDP1CA12CA9CA1
SCHEMBL30138955 0.85 TDP1 (0.44) CYP3A4TDP1CA12CA9CA1
SCHEMBL28902398 0.79 LCK (0.41) CYP3A4TDP1CA12CA9CA1
SCHEMBL28906236 0.76 CYP3A4 (0.42) CYP3A4TDP1NQO2KDM4EGAA
SCHEMBL5684735 0.75 CA1 (0.41) CYP3A4TDP1CA12CA9CA1
SCHEMBL56425 0.75 CA1 (0.50) CYP3A4TDP1CA12CA9CA1
SCHEMBL13593792 0.75 CA1 (0.38) CYP3A4TDP1CA12CA9CA1
SCHEMBL19009974 0.74 CYP3A4 (0.37) CYP3A4TDP1CA12CA9CA1
SCHEMBL1042656 0.74 TUBB4A (0.42) CYP3A4TDP1CA12CA9CA1
SCHEMBL8459532 0.73 CA1 (0.48) CYP3A4TDP1CA12CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115433227-A Multidentate phosphine coordinated copper trihalo tri-type complex, and synthesis method and application thereof 黑龙江大学 2022-12-06 CN disclosed