Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | XDH | P47989 | 1/20 | 0.68 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25327273 | 0.90 | MAPT (0.89) | APPMAPTMEN1MAPK1KMT2A | |
| SCHEMBL25200346 | 0.90 | APP (1.00) | APPMAPTMEN1MAPK1KMT2A | |
| SCHEMBL25202885 | 0.90 | APP (1.00) | APPMAPTMEN1MAPK1KMT2A | |
| SCHEMBL17220889 | 0.88 | MAPT (0.80) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL17220887 | 0.88 | MAPT (0.80) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9986620 | 0.87 | ABCG2 (0.84) | APPMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9986622 | 0.87 | ABCG2 (0.84) | APPMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28906337 | 0.86 | NR1H4 (0.70) | APPMAPTMEN1MAPK1KMT2A | |
| SCHEMBL5082149 | 0.85 | MAPT (1.00) | APPMAPTMEN1MAPK1KMT2A | |
| SCHEMBL5082144 | 0.85 | MAPT (1.00) | APPMAPTMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304513-A | Chalcone derivative with anti-inflammatory activity and synthesis method and application thereof | 湖北科技学院 | 2022-11-08 | — | — | CN | disclosed |