Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330391 | 0.88 | ABCG2 (0.70) | ABCG2MAOBMAPTMEN1KMT2A | |
| SCHEMBL7330385 | 0.88 | ABCG2 (0.70) | ABCG2MAOBMAPTMEN1KMT2A | |
| SCHEMBL17220887 | 0.87 | MAPT (0.80) | NR1H4ABCG2MAOBMAOAMAPT | |
| SCHEMBL17220889 | 0.87 | MAPT (0.80) | NR1H4ABCG2MAOBMAOAMAPT | |
| SCHEMBL28906330 | 0.86 | APP (0.81) | ABCG2MAOBMAOAMAPTKDM4E | |
| SCHEMBL25195133 | 0.83 | MAOB (0.77) | ABCG2MAOBMAOAMAPTMEN1 | |
| SCHEMBL30382414 | 0.83 | MAOB (0.77) | ABCG2MAOBMAOAMAPTMEN1 | |
| SCHEMBL25191354 | 0.83 | MAOB (0.77) | ABCG2MAOBMAOAMAPTMEN1 | |
| SCHEMBL14691342 | 0.82 | NR1H4 (1.00) | NR1H4ABCG2MAOBMAOAMAPT | |
| SCHEMBL25327273 | 0.82 | MAPT (0.89) | NR1H4ABCG2MAOBMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304513-A | Chalcone derivative with anti-inflammatory activity and synthesis method and application thereof | 湖北科技学院 | 2022-11-08 | — | — | CN | disclosed |