Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | MAOA | P21397 | 1/20 | 0.72 |
| ▸ | MAOB | P27338 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | AR | P10275 | 2/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2376112 | 0.87 | MAPT (0.74) | MAPTNPSR1L3MBTL1MAOAMAOB | |
| SCHEMBL7956659 | 0.87 | MAPT (0.74) | MAPTNPSR1L3MBTL1MAOAMAOB | |
| SCHEMBL19603333 | 0.84 | MAPT (1.00) | MAPTNPSR1L3MBTL1MAOAMAOB | |
| SCHEMBL5424561 | 0.84 | MAOB (0.74) | MAPTNPSR1L3MBTL1MAOAMAOB | |
| SCHEMBL5424563 | 0.84 | MAOB (0.74) | MAPTNPSR1L3MBTL1MAOAMAOB | |
| SCHEMBL28906329 | 0.83 | AR (0.76) | MAPTL3MBTL1MAOAMAOBAR | |
| SCHEMBL2374997 | 0.81 | MAPT (0.70) | MAPTNPSR1L3MBTL1MAOAMAOB | |
| SCHEMBL2374989 | 0.81 | MAPT (0.70) | MAPTNPSR1L3MBTL1MAOAMAOB | |
| SCHEMBL4119024 | 0.81 | GUSB (0.72) | MAPTMAOAMAOBSMN1; SMN2AR | |
| SCHEMBL4119027 | 0.81 | GUSB (0.72) | MAPTMAOAMAOBSMN1; SMN2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304513-A | Chalcone derivative with anti-inflammatory activity and synthesis method and application thereof | 湖北科技学院 | 2022-11-08 | — | — | CN | disclosed |