Fluoride

Fluoride

SCHEMBL28906348

F.F.F.O=Cc1ccc(Br)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.50
HSD17B10 Q99714 1/20 0.50
ALDH5A1 P51649 1/20 0.50
ABAT P80404 1/20 0.50
ALDH1A1 P00352 6/20 0.48
TYR P14679 1/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP2A13 Q16696 1/20 0.44
ALDH1A3 P47895 3/20 0.41
ALDH3A1 P30838 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6034 0.97
SCHEMBL17231886 0.97 CYP2A6 (0.52) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
Water SCHEMBL28171939 0.94 CYP2A6 (0.50) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
SCHEMBL27737702 0.94
Hydrogen Sulfide SCHEMBL28226400 0.94 CYP2A6 (0.50) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
Ammonia Solution, Strong SCHEMBL6557011 0.94 CYP2A6 (0.50) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
Hydrochloric Acid SCHEMBL11785011 0.94 CYP2A6 (0.50) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
Benzene SCHEMBL28625494 0.92 ALDH1A1 (0.60) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
Ethylene SCHEMBL5407508 0.92 CYP2A6 (0.48) CYP2A6HSD17B10ALDH5A1ABATALDH1A1
Bromide SCHEMBL27529310 0.92 CYP2A6 (0.48) CYP2A6HSD17B10ALDH5A1ABATALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112262128-A Method for forming aryl carbon-nitrogen bond by illumination and photoreactor for carrying out the reaction 科罗拉多州立大学研究基金会 2021-01-22 CN disclosed